PsiThera is advancing a paradigm shift in biotechnology by pioneering a physics-driven approach to drug design that is tightly coupled to chemistry and biology research and development. Our QUAISAR platform is purpose-built to develop novel small molecule therapeutics to address biologically and genetically validated but previously intractable protein targets.
Our capabilities are driven by our industry-leading QUAISAR computational platform, which combines preeminent physics-based simulation tools with machine learning to generate unprecedented predictive power that can tackle previously intractable challenges. The tight integration of the QUAISAR platform with our broad experimental capabilities and deep drug discovery experience enables the rapid design and optimization of new drugs to address a wide range of targets for diseases with high unmet need.
PsiThera’s name and logo originate from the penultimate Greek letter ᴪ (spelled Psi and pronounced “sī”), which represents the wave function in quantum physics. Psi fully describes matter at the atomic level. The conceptual and mathematical underpinnings of the wave function revolutionized our understanding of the physical world. Psi is the foundation for how we design better drugs at PsiThera, atom by atom. Watch “A Better Way To Picture Atoms” on YouTube to learn more about Psi.
Designing Better Medicines, Atom by Atom
PsiThera tackles today’s vast chemical space and challenging disease targets with our proprietary quantum physics-based simulations, bespoke AI/ML methods, in-house high-performance supercomputing and advanced biophysical methods to perform accurate, all-atom, highly predictive simulations at scale.
By combining computational breakthroughs with project-specific experimental data, our integrated team of chemists, biologists, physicists, biophysicists, computational scientists, software engineers and parallel computing can produce the most accurate three-dimensional dynamic atomistic model simulations to break through historical bottlenecks that have prevented the effective discovery of therapeutics.
We believe our end-to-end expertise, spanning the critical dimensions of both computation and lab-based experiments, will lead to the rapid design and discovery of new medicines that will improve the lives of patients.
Our Values
Patient-Inspired
Our ultimate goal at Psivant is to create better therapeutics for patients with unmet medical needs. We are constantly improving the drug discovery process by integrating advanced computational technologies to improve the probability that our therapeutic programs will progress from our labs to the clinic and to broader patient populations. We are driven to make meaningful improvements to the health of people around the world by designing better therapeutics, atom by atom.
Perseverant
We are committed to designing better therapeutics by integrating best-in-class predictive methods with laboratory expertise, which allows us to tackle previously intractable challenges. An unwavering pursuit of scientific advancement is at the heart of our approach, which enabled us to drug STING (stimulator of interferon genes) — a central regulator of the innate immune system and a previously intractable therapeutic target. Our determination and tenacity drive our team to break down barriers and do whatever it takes to bring our therapeutic programs to patients in need.
Synergistic
Psivant has built a world-class team with diverse experience across disciplines ranging from the lab (biology, chemistry, biophysics, and structural biology) to the computer (physics, cheminformatics, machine learning, and data science). This continuum of complementary skills and thinking enables our team to overcome challenges that may appear insurmountable to an individual. Our determination to bring innovative therapeutics to patients motivates our team to think out of the box and figure out how complementary skills on the team can synergize to solve the biggest challenges in drug discovery. We have created a work environment and organizational structure where the team is far greater than the sum of the parts.
Supportive
We encourage everyone at Psivant to share ideas and voice opinions openly as we test hypotheses and work as a team to find the best path forward in our therapeutic programs. We recognize that we are trying to solve some of the greatest challenges to improve human health and there will be moments when we don’t have all other information required to arrive at consensus – but we’re OK with that. We support each other to work through these challenges and make decisions to drive our drug discovery projects toward the clinic.
Intrepid
We fearlessly challenge conventional assumptions, with conviction that Psivant is advancing a paradigm shift in drug discovery. We relish our role as pioneers in a new class of drug hunters. Our computationally-driven insights about biological systems tightly coupled with expertise in the lab enables us to blaze new trails toward designing better therapeutic molecules and treating previously intractable diseases.
Inclusive
We are committed to receptivity and diversity in terms of people, ideas, cultures, and opinions. We strive to cross scientific boundaries by integrating synergistic disciplines including physics, chemistry, biology, data science, and software engineering. Openness to diverse ideas from all who wish to contribute keeps us at the forefront of innovation and maximizes our probability of solving hard problems. At Psivant, all ideas are welcome!
